[IEEE-bhpjobs] The Visualization Friday Forum

[Walter Heger]

The Visualization Friday Forum

Spring 2005 * Noon-1pm * D106 LSRC



April 22 - Gaming, Simulation, and Learning
Jeff Taekman
Department of Anesthesiology





April 29 - Protein Protein Interfaces
Johannes Rudolph
Department of Biochemistry

Protein-protein interactions form the basis for most cellular processes,
including events intimately linked to human diseases.  Despite their
importance, our understanding of the molecular details of protein-protein
interactions remains poor, lagging far behind that of protein folding and
structure.  Descriptors and visual tools that describe protein interfaces
are needed to discover the universal rules expected to govern the
specificity and efficiency of protein-protein association.  Recently, we
have used tools from computational geometry to define a protein interface
surface.  We can define a hierarchy of structures on this interface surface.
Primary structure describes adjacencies, either on one side of the interface
or across the interface.  Secondary structure describes small recurring
geometric motifs.  Tertiary structure describes the landscape of these
motifs.  Here we describe the visualization of these primary and secondary
structures of protein interfaces.

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Ref:

http://vis.duke.edu/FridayForum/05Spring.htm